Antimicrobial activity of some honey samples against. That honey has antibacterial properties has been known for more than a century 1. The antibacterial activity of honey has been known since the 19th century. The antibacterial activity of honey and its role in treating diseases. This is a term that has been widely used since as a measure of the antibacterial activity of honey. Zaat1 1department of medical microbiology, center for infection and immunity amsterdam cinima, academic medical center, university of amsterdam, amsterdam, the. This later type of activity is characteristic of honeys from australasia e. Despite the multi floral and huge honey production in the region, there are no studies that evaluate the antibacterial activity of honey against multidrug resistant bacteria. Antimicrobial definition is destroying or inhibiting the growth of microorganisms and especially pathogenic microorganisms. Antimicrobial activity of a novel bioengineered honey. The high antimicrobial activity of honey has been attributed to its properties such as osmotic effect, acidity, hydrogen peroxide and other phytochemical factors, further more, it appears that the honey from certain plants has. A sugar solution resembling honey in its high sugar content was made.
Antimicrobial activity of honey 4 of two hives of tetragonisca angustula only from each of sites 1, 2, 4, 5 and 6. The antibacterial activity of honey and its role in treating diseases disclaimer. Although it has been used as a medicine since ancient times in many cultures 2,3, in its ancient usage there was no recognition of its antibacterial properties it was just known to be an effective remedy. Comparison of honey vs silver for antibacterial activity. Exploring the antibacterial properties of honey and its. The use of honey as a therapeutic substance has been rediscovered by the medical profession in more recent times, and it is gaining acceptance as an antibacterial agent for the treatment of ulcers and bed sores, and other infections resulting from burns and wounds. In chile, the most emblematic flower honey, both for its abundance and sensory characteristics, is ulmo honey eucriphya cordifolia and quillay honey quillaja. Particularly, good results were achieved in the case of application of this product for therapy of infected, difficult to heal wounds. Full text on the antibacterial effects of manuka honey. It is generally accepted that mic measurement in broth is a more sensitive and quantitatively accurate method with which to study the antimicrobial activity of honey compared to agar well.
However, the newly identified honeys may have advantages over or similarities with manuka honey due to enhanced antimicrobial activity, local production thus availability, and greater selectivity. Antibacterial activity of bee honey and its therapeutic usefulness against escherichia coli o157. Unlike manuka honey, the activity of ulmo honey is largely due to h 2 o 2 production. Comparison of honey vs silver for antibacterial activity 2 background honey is known for its wound healing and antimicrobial properties, however the bioactivity of the honey is dependent on many factors such as the geographical location and the floral source from which the honey is derived sherlock et al. Antimicrobial activity of some honey samples against pathogenic bacteria s. The skin serves many functions and externally it often defines our emotional well being through appearance. Geographical variation in honeys antimicrobial activity. Honey antibacterial activity longdom publishing sl. In this report, a raw pure honey authenticated sample, claimed as meadow honey, collected from the central eastern part of sudan, did not show any significant antibacterial activity against the tested bacteria referenced and. The remarkably rapid effect of honey in cleaning up wounds, an autolyic debridement in which adherent dead cells and fibrin clots, a rich breeding ground for bacteria, are digested free by protease activity in the wound tissue and lift off easily, is due to a combination of. The present study was performed to clarify the possible causes of the antimicrobial activity of honey. Citescore values are based on citation counts in a given year e.
However, another kind of honey, called nonperoxide honey viz. The antibacterial activity of honey can be divided into hydrogen peroxide and nonhydrogen peroxidederived activity. Antimicrobial activity of medicinal plants against human pathogenic bacteria 657 inflammatory properties of plants mahesh and satish, 2008. A number of enzymes such as invertase, amylase and glucose oxidase have been found in honey. This is not surprising considering that it is only since the latter part of the last century that. Rachel s newby 1, matthew dryden 2, 3, raymond n allan 1, 4, rami j salib 3, 5.
Various researchers have shown that honey exerts an antibacterial activity against various organisms, including both grampositive and gramnegative bacteria. Four collected honey varieties exhibited antibacterial activity, while the strongest inhibitory activity was demonstrated by honey 2 at 75% vv. Evaluation of antibacterial activity of honey against. Kumarasamy botany wing dde annamalai university, annamalai nagar 608002, tamil nadu, india email address. Antimicrobial resistance amr is an increasing clinical problem precipitated by the inappropriate use of. The antibacterial activity of honey on staphylococcus. Pdf on mar 15, 2017, piotr szweda and others published antimicrobial activity of honey find, read and cite all the research you need on. Rs honey killed bacillus subtilis, escherichia coli and pseudomonas aeruginosa within 2 hours, whereas. The antibacterial activity of honey appears to have been reported first by van ketel in 1892. The hydrogen peroxide is a potent antimicrobial agent, produced mainly during glucose oxidation catalyzed by the action of the bee enzyme, glucose oxidase, which is. Thus, the chemical identity, quantitative contribution, and origin of the different honey antimicrobial substances remain to a great extent unknown. It was used to overcome liver, cardiovascular and gastrointestinal problems and for treatment of some types of infectious disease. Antibacterial activity of bee honey and its therapeutic. Honey chemical composition is related to the plant species where nectar is collected by honeybees.
Two major medicinal honeys have different mechanisms of. However, another kind of honey, called nonperoxide honey. Explanation of the antibacterial activity of honey osmotic effect honey is a saturated or supersaturated solution of sugars, the water content usually being only 1521% by weight124. Antimicrobial effect of different types of honey on. The hydrogen peroxide has been described as the main compound responsible by the antibacterial activity of honeys. Chromatography quick column chromatography a column was tightly packed with 500 g silica gel 60 g 0. Recently, the potent activity of honey against antibioticresistant bacteria has further increased the interest for application of honey, but incomplete knowledge of the antibacterial activity is a major obstacle for clinical applicability. However, honey as a raw natural product could lose part of its quality due to many direct or indirect effects.
The content of this document is for general information purposes only and does not constitute, nor does it intend to constitute, medical or other professional advice. By strict definition, the word antibiotic refers to substances produced by microorganisms. The antimicrobial activity of honey, bee pollen loads and beeswax from slovakia article pdf available in archives of biological sciences 643. Honey has been used as a medicine since ancient times in many cultures and is still used in folk medicine. This is due to the variation of distribution among the fractions of the different honey types. Pdf the antimicrobial activity of honey, bee pollen. International journal of antimicrobial agents elsevier.
The mic minimum inhibitory concentration of honey was found to range from 1. The antimicrobial activity in most honeys is due to the enzymatic production of hydrogen peroxide. Honey is increasingly valued for its antibacterial activity, but knowledge regarding the mechanism of action is still incomplete. Reviews on the effects of honey in medicine and its properties was further studied, because as. Antimicrobial effect of honey from different geographical locations. Agar inhibition assay showed kelulut honey to possess highest total antibacterial activity against s.
Antimicrobial activity of medicinal plants against human. Antibacterial activity of different blossom honeys. Several physical, biochemical and antioxidant properties of two nigerian stingless bee honey varieties melipona sp. Two major medicinal honeys have different mechanisms of bactericidal activity paulus h. Honey, a bee product, offers a broadspectrum of biological properties including antimicrobial and wound healing activity 1. The antibacterial activity of honey research commons university. Kamal3 1 animal health research institute, bacteriology department, bee keeping department, agricultural. Chilean beekeeping is characterized by a variety of honey types, some unique, due to a high participation of endemic and native species. Nature and origin of the antibacterial substances in honey. Dissecting the antimicrobial composition of honey mdpi.
Evaluation of bactericidal activity of hannon honey on slowly growing bacteria in the chemostat najib sufya,1 noora matar,1 rawanda kaddura,1 abdulaziz zorgani2 1department of microbiology and immunology, faculty of pharmacy, 2department of microbiology and immunology, faculty of medicine, university of tripoli, tripoli, libya abstract. Antibacterial activity of honey majmaah university. Hence integration of traditional medicine like honey and modern medicine could be a best option in the treatment of patients infected with drug resistant bacteria. Microbiologicalantibacterial activities and antioxidant. Comparison of the antimicrobial activity of honey produced. Three types of libyan honey antioxidant activity of the honey varieties were ziziphus lotus honey,arbutus pavarii andceratania measured in terms of hydrogen donating or radicalsiliqua honey were collected from the green mountain scavenging ability using the stable dpph method as during spring season, 2012. The antibacterial activity of the cme, cde and che extracts were then assayed for antibacterial activity by the agar well diffusion and microbroth dilution assays. Antimicrobial definition of antimicrobial by merriamwebster.
Honey was found to be effective in the treatment of dyspepsia and of gastric and duodenal ulcers, which is mainly caused by infection with helicobacter pylori sato and miyata, 2000. Antimicrobial effect of different types of honey on staphylococcus. Research paper antibacterial activity of a cardanol from. The antibacterial activity of honey obtained from different locations in enugu north and southnsukka and ugwuaji nigeria on streptococcus pyogenes, escherichia coli and staphylococcus aureus isolated from wound swabs collected from university of nigeria teaching hospital unth were studied. The assay uses bacteria which can vary in their relative sensitivity to the factors in the manuka honey and to phenol. Antibacterial activity of honey against methicillin. Work on the antibacterial activity of honey has been going on since the eighteenth century. The word antimicrobial was derived from the greek words anti against, mikros little and bios life and refers to all agents that act against microbial organisms. Honey is antibacterial and can prevent growth of most types of bacteria.
The inhibine number involves a scale of 1 to 5 representing sequential dilutions of honey in 5% steps, from 25% to 5%. Of the solids in honey, 84% is a mixture of the monosaccharides fructose and glucose125. This is not synonymous with antibiotics, a similar term derived from the greek word anti against and biotikos concerning life. This study aims to compare the effects of five types of honey both imported and local saudi honey against staphylococcus aureus. All isolates showed a high frequency of resistance to tetracycline. The antimicrobial activity and microbiological safety of.
The antibacterial activity of honey and its role in. Evaluation of bactericidal activity of hannon honey on. Both raw and processed honey showed the inhibitory effects which were inherent mostly in all selected test organisms except e. The antibacterial properties of honey have been well documented. Honey has had a valued place in traditional medicine for centuries. Besides, evidences of antibiotic activity of honey applications directly, orally taken honey may also serve as potential candidate for future. In the manuka honey 90% of the activity was found in the acidic fraction, in the rape honey the major part of the activity was in. The antimicrobial activities of both honey and this solution towards 21 types of bacteria and two types of fungi were examined. The antibacterial activity of honey is mainly due to inhibines in honey. The purpose of the present study was to clarify these. The level of leptosin, a glycoside found exclusively in leptospermum honey.
Antimicrobial activity of a novel bioengineered honey against nontypeable haemophilus influenzae biofilms. Causes of the antimicrobial activity of honey springerlink. Reports of antimicrobial activity of honey experimental approach the antibacterial activity of honey appears to have been reported first by van ketel in 1892 cited by dustmann35. The significant activity may be due to the property of honey which. Several components are known to contribute the nonperoxide activity, such as the presence of methyl syringate and methylglyoxal, which have been extensively studied in. The high healthpromoting properties of honey have been. Considering honey as a therapeutic, antimicrobial agent special attention deserves manuka honey.